X-ray radiation and its application. Brief description of x-ray radiation. The use of x-rays in medicine
Brief description of X-ray radiation
X-rays are electromagnetic waves (flux of quanta, photons), the energy of which is located on the energy scale between ultraviolet radiation and gamma radiation (Fig. 2-1). X-ray photons have an energy of 100 eV to 250 keV, which corresponds to radiation with a frequency of 3×10 16 Hz to 6×10 19 Hz and a wavelength of 0.005-10 nm. The electromagnetic spectra of x-rays and gamma rays overlap to a large extent.
Rice. 2-1. Electromagnetic radiation scale
The main difference between these two types of radiation is the way they occur. X-rays are obtained with the participation of electrons (for example, during the deceleration of their flow), and gamma rays - with the radioactive decay of the nuclei of some elements.
X-rays can be generated during deceleration of an accelerated flow of charged particles (the so-called bremsstrahlung) or when high-energy transitions occur in the electron shells of atoms (characteristic radiation). Medical devices use X-ray tubes to generate X-rays (Figure 2-2). Their main components are a cathode and a massive anode. The electrons emitted due to the difference in electrical potential between the anode and the cathode are accelerated, reach the anode, upon collision with the material of which they are decelerated. As a result, bremsstrahlung X-rays are produced. During the collision of electrons with the anode, the second process also occurs - electrons are knocked out of the electron shells of the anode atoms. Their places are occupied by electrons from other shells of the atom. During this process, a second type of X-ray radiation is generated - the so-called characteristic X-ray radiation, the spectrum of which largely depends on the anode material. Anodes are most often made from molybdenum or tungsten. There are special devices for focusing and filtering X-rays in order to improve the resulting images.
Rice. 2-2. Scheme of the X-ray tube device:
The properties of X-rays that predetermine their use in medicine are penetrating, fluorescent and photochemical effects. The penetrating power of X-rays and their absorption by the tissues of the human body and artificial materials are the most important properties that determine their use in radiation diagnostics. The shorter the wavelength, the greater the penetrating power of X-rays.
There are "soft" X-rays with low energy and radiation frequency (respectively, with the largest wavelength) and "hard" X-rays with high photon energy and radiation frequency, having a short wavelength. The wavelength of X-ray radiation (respectively, its "rigidity" and penetrating power) depends on the magnitude of the voltage applied to the X-ray tube. The higher the voltage on the tube, the greater the speed and energy of the electron flow and the shorter the wavelength of the x-rays.
During the interaction of X-ray radiation penetrating through the substance, qualitative and quantitative changes occur in it. The degree of absorption of X-rays by tissues is different and is determined by the density and atomic weight of the elements that make up the object. The higher the density and atomic weight of the substance of which the object (organ) under study consists, the more X-rays are absorbed. The human body contains tissues and organs of different densities (lungs, bones, soft tissues, etc.), which explains the different absorption of X-rays. The visualization of internal organs and structures is based on the artificial or natural difference in the absorption of X-rays by various organs and tissues.
To register the radiation that has passed through the body, its ability to cause fluorescence of certain compounds and to have a photochemical effect on the film is used. For this purpose, special screens for fluoroscopy and photographic films for radiography are used. In modern X-ray machines, special systems of digital electronic detectors - digital electronic panels - are used to register attenuated radiation. In this case, X-ray methods are called digital.
Because of the biological effects of x-rays, it is essential to protect patients during the examination. This is achieved
the shortest possible exposure time, the replacement of fluoroscopy with radiography, the strictly justified use of ionizing methods, protection by shielding the patient and staff from exposure to radiation.
Brief description of x-ray radiation - concept and types. Classification and features of the category "Brief characteristics of X-ray radiation" 2017, 2018.
X-RAY RADIATION
invisible radiation capable of penetrating, albeit to varying degrees, all substances. It is electromagnetic radiation with a wavelength of about 10-8 cm. Like visible light, X-rays cause blackening of photographic film. This property is of great importance for medicine, industry and scientific research. Passing through the object under study and then falling on the film, X-ray radiation depicts its internal structure on it. Since the penetrating power of X-ray radiation is different for different materials, parts of the object that are less transparent to it give brighter areas in the photograph than those through which the radiation penetrates well. Thus, bone tissues are less transparent to x-rays than the tissues that make up the skin and internal organs. Therefore, on the radiograph, the bones will be indicated as lighter areas and the fracture site, which is more transparent for radiation, can be quite easily detected. X-ray imaging is also used in dentistry to detect caries and abscesses in the roots of teeth, as well as in industry to detect cracks in castings, plastics and rubbers. X-rays are used in chemistry to analyze compounds and in physics to study the structure of crystals. An X-ray beam passing through a chemical compound causes a characteristic secondary radiation, the spectroscopic analysis of which allows the chemist to determine the composition of the compound. When falling on a crystalline substance, an X-ray beam is scattered by the atoms of the crystal, giving a clear, regular pattern of spots and stripes on a photographic plate, which makes it possible to establish the internal structure of the crystal. The use of X-rays in cancer treatment is based on the fact that it kills cancer cells. However, it can also have an undesirable effect on normal cells. Therefore, extreme caution must be exercised in this use of X-rays. X-ray radiation was discovered by the German physicist W. Roentgen (1845-1923). His name is immortalized in some other physical terms associated with this radiation: the international unit of the dose of ionizing radiation is called the roentgen; a picture taken with an x-ray machine is called a radiograph; The field of radiological medicine that uses x-rays to diagnose and treat diseases is called radiology. Roentgen discovered radiation in 1895 while a professor of physics at the University of Würzburg. While conducting experiments with cathode rays (electron flows in discharge tubes), he noticed that a screen located near the vacuum tube, covered with crystalline barium cyanoplatinite, glows brightly, although the tube itself is covered with black cardboard. Roentgen further established that the penetrating power of the unknown rays he discovered, which he called X-rays, depended on the composition of the absorbing material. He also imaged the bones of his own hand by placing it between a cathode ray discharge tube and a screen coated with barium cyanoplatinite. Roentgen's discovery was followed by experiments by other researchers who discovered many new properties and possibilities for using this radiation. A great contribution was made by M. Laue, W. Friedrich and P. Knipping, who demonstrated in 1912 the diffraction of X-rays when it passes through a crystal; W. Coolidge, who in 1913 invented a high-vacuum X-ray tube with a heated cathode; G. Moseley, who established in 1913 the relationship between the wavelength of radiation and the atomic number of an element; G. and L. Braggi, who received the Nobel Prize in 1915 for developing the fundamentals of X-ray diffraction analysis.
OBTAINING X-RAY RADIATION
X-ray radiation occurs when electrons moving at high speeds interact with matter. When electrons collide with atoms of any substance, they quickly lose their kinetic energy. In this case, most of it is converted into heat, and a small fraction, usually less than 1%, is converted into X-ray energy. This energy is released in the form of quanta - particles called photons that have energy but have zero rest mass. X-ray photons differ in their energy, which is inversely proportional to their wavelength. With the conventional method of obtaining x-rays, a wide range of wavelengths is obtained, which is called the x-ray spectrum. The spectrum contains pronounced components, as shown in Fig. 1. A wide "continuum" is called a continuous spectrum or white radiation. The sharp peaks superimposed on it are called characteristic x-ray emission lines. Although the entire spectrum is the result of collisions of electrons with matter, the mechanisms for the appearance of its wide part and lines are different. A substance consists of a large number of atoms, each of which has a nucleus surrounded by electron shells, and each electron in the shell of an atom of a given element occupies a certain discrete energy level. Usually these shells, or energy levels, are denoted by the symbols K, L, M, etc., starting from the shell closest to the nucleus. When an incident electron of sufficiently high energy collides with one of the electrons bound to the atom, it knocks that electron out of its shell. The empty space is occupied by another electron from the shell, which corresponds to a higher energy. This latter gives off excess energy by emitting an X-ray photon. Since the shell electrons have discrete energy values, the resulting X-ray photons also have a discrete spectrum. This corresponds to sharp peaks for certain wavelengths, the specific values of which depend on the target element. The characteristic lines form K-, L- and M-series, depending on which shell (K, L or M) the electron was removed from. The relationship between the wavelength of X-rays and the atomic number is called Moseley's law (Fig. 2).
If an electron collides with a relatively heavy nucleus, then it slows down, and its kinetic energy is released in the form of an X-ray photon of approximately the same energy. If he flies past the nucleus, he will lose only part of his energy, and the rest will be transferred to other atoms that fall in his way. Each act of energy loss leads to the emission of a photon with some energy. A continuous X-ray spectrum appears, the upper limit of which corresponds to the energy of the fastest electron. This is the mechanism for the formation of a continuous spectrum, and the maximum energy (or minimum wavelength) that fixes the boundary of the continuous spectrum is proportional to the accelerating voltage, which determines the speed of the incident electrons. The spectral lines characterize the material of the bombarded target, while the continuous spectrum is determined by the energy of the electron beam and practically does not depend on the target material. X-rays can be obtained not only by electron bombardment, but also by irradiating the target with X-rays from another source. In this case, however, most of the energy of the incident beam goes into the characteristic X-ray spectrum, and a very small fraction of it falls into the continuous spectrum. Obviously, the incident X-ray beam must contain photons whose energy is sufficient to excite the characteristic lines of the bombarded element. The high percentage of energy per characteristic spectrum makes this method of X-ray excitation convenient for scientific research.
X-ray tubes. In order to obtain X-ray radiation due to the interaction of electrons with matter, it is necessary to have a source of electrons, means of accelerating them to high speeds, and a target capable of withstanding electron bombardment and producing X-ray radiation of the desired intensity. The device that has all this is called an x-ray tube. Early explorers used "deep vacuum" tubes such as today's discharge tubes. The vacuum in them was not very high. Discharge tubes contain a small amount of gas, and when a large potential difference is applied to the electrodes of the tube, the gas atoms turn into positive and negative ions. The positive ones move towards the negative electrode (cathode) and, falling on it, knock electrons out of it, and they, in turn, move towards the positive electrode (anode) and, bombarding it, create a stream of X-ray photons. In the modern X-ray tube developed by Coolidge (Fig. 3), the source of electrons is a tungsten cathode heated to a high temperature. The electrons are accelerated to high speeds by the high potential difference between the anode (or anticathode) and the cathode. Since the electrons must reach the anode without colliding with atoms, a very high vacuum is required, for which the tube must be well evacuated. This also reduces the probability of ionization of the remaining gas atoms and the associated side currents.
The electrons are focused on the anode by a specially shaped electrode surrounding the cathode. This electrode is called the focusing electrode and together with the cathode forms the "electronic searchlight" of the tube. The anode subjected to electron bombardment must be made of a refractory material, since most of the kinetic energy of the bombarding electrons is converted into heat. In addition, it is desirable that the anode be made of a material with a high atomic number, since the x-ray yield increases with increasing atomic number. Tungsten, whose atomic number is 74, is most often chosen as the anode material. The design of X-ray tubes can be different depending on the application conditions and requirements.
X-RAY DETECTION
All methods for detecting X-rays are based on their interaction with matter. Detectors can be of two types: those that give an image, and those that do not. The former include X-ray fluorography and fluoroscopy devices, in which the X-ray beam passes through the object under study, and the transmitted radiation enters the luminescent screen or film. The image appears due to the fact that different parts of the object under study absorb radiation in different ways - depending on the thickness of the substance and its composition. In detectors with a luminescent screen, the X-ray energy is converted into a directly observable image, while in radiography it is recorded on a sensitive emulsion and can only be observed after the film has been developed. The second type of detectors includes a wide variety of devices in which the X-ray energy is converted into electrical signals that characterize the relative intensity of the radiation. These include ionization chambers, a Geiger counter, a proportional counter, a scintillation counter, and some special detectors based on cadmium sulfide and selenide. Currently, scintillation counters can be considered the most efficient detectors, which work well in a wide energy range.
see also PARTICLE DETECTORS . The detector is selected taking into account the conditions of the problem. For example, if it is necessary to accurately measure the intensity of diffracted X-ray radiation, then counters are used that allow measurements to be made with an accuracy of fractions of a percent. If it is necessary to register a lot of diffracted beams, then it is advisable to use X-ray film, although in this case it is impossible to determine the intensity with the same accuracy.
X-RAY AND GAMMA DEFECTOSCOPY
One of the most common applications of X-rays in industry is material quality control and flaw detection. The x-ray method is non-destructive, so that the material being tested, if found to meet the required requirements, can then be used for its intended purpose. Both x-ray and gamma flaw detection are based on the penetrating power of x-rays and the characteristics of its absorption in materials. Penetrating power is determined by the energy of X-ray photons, which depends on the accelerating voltage in the X-ray tube. Therefore, thick samples and samples from heavy metals, such as gold and uranium, require an X-ray source with a higher voltage for their study, and for thin samples, a source with a lower voltage is sufficient. For gamma-ray flaw detection of very large castings and large rolled products, betatrons and linear accelerators are used, accelerating particles to energies of 25 MeV and more. The absorption of X-rays in a material depends on the thickness of the absorber d and the absorption coefficient m and is determined by the formula I = I0e-md, where I is the intensity of the radiation transmitted through the absorber, I0 is the intensity of the incident radiation, and e = 2.718 is the base of natural logarithms. For a given material, at a given wavelength (or energy) of X-rays, the absorption coefficient is a constant. But the radiation of an X-ray source is not monochromatic, but contains a wide range of wavelengths, as a result of which the absorption at the same thickness of the absorber depends on the wavelength (frequency) of the radiation. X-ray radiation is widely used in all industries associated with the processing of metals by pressure. It is also used to test artillery barrels, foodstuffs, plastics, to test complex devices and systems in electronic engineering. (Neutronography, which uses neutron beams instead of X-rays, is used for similar purposes.) X-rays are also used for other purposes, such as examining paintings to determine their authenticity or detecting additional layers of paint on top of the main layer.
X-RAY DIFFRACTION
X-ray diffraction provides important information about solids—their atomic structure and crystal form—as well as about liquids, amorphous bodies, and large molecules. The diffraction method is also used for accurate (with an error of less than 10-5) determination of interatomic distances, detection of stresses and defects, and for determining the orientation of single crystals. The diffraction pattern can identify unknown materials, as well as detect the presence of impurities in the sample and determine them. The importance of the X-ray diffraction method for the progress of modern physics can hardly be overestimated, since the modern understanding of the properties of matter is ultimately based on data on the arrangement of atoms in various chemical compounds, on the nature of the bonds between them, and on structural defects. The main tool for obtaining this information is the X-ray diffraction method. X-ray diffraction crystallography is essential for determining the structures of complex large molecules, such as those of deoxyribonucleic acid (DNA), the genetic material of living organisms. Immediately after the discovery of X-rays, scientific and medical interest was concentrated both on the ability of this radiation to penetrate through bodies, and on its nature. Experiments on the diffraction of X-rays on slits and diffraction gratings showed that it belongs to electromagnetic radiation and has a wavelength of the order of 10-8-10-9 cm. Even earlier, scientists, in particular W. Barlow, guessed that the regular and symmetrical shape of natural crystals is due to the ordered arrangement of atoms that form the crystal. In some cases, Barlow was able to correctly predict the structure of a crystal. The value of the predicted interatomic distances was 10-8 cm. The fact that the interatomic distances turned out to be of the order of the X-ray wavelength made it possible in principle to observe their diffraction. The result was the idea for one of the most important experiments in the history of physics. M. Laue organized an experimental test of this idea, which was carried out by his colleagues W. Friedrich and P. Knipping. In 1912, the three of them published their work on the results of X-ray diffraction. Principles of X-ray diffraction. To understand the phenomenon of X-ray diffraction, one must consider in order: firstly, the spectrum of X-rays, secondly, the nature of the crystal structure and, thirdly, the phenomenon of diffraction itself. As mentioned above, the characteristic X-ray radiation consists of a series of spectral lines of a high degree of monochromaticity, determined by the anode material. With the help of filters, you can select the most intense of them. Therefore, by choosing the anode material in an appropriate way, it is possible to obtain a source of almost monochromatic radiation with a very precisely defined wavelength value. The wavelengths of the characteristic radiation typically range from 2.285 for chromium to 0.558 for silver (the values for the various elements are known to six significant figures). The characteristic spectrum is superimposed on a continuous "white" spectrum of much lower intensity, due to the deceleration of the incident electrons in the anode. Thus, two types of radiation can be obtained from each anode: characteristic and bremsstrahlung, each of which plays an important role in its own way. Atoms in the crystal structure are located at regular intervals, forming a sequence of identical cells - a spatial lattice. Some lattices (for example, for most ordinary metals) are quite simple, while others (for example, for protein molecules) are quite complex. The crystal structure is characterized by the following: if one shifts from some given point of one cell to the corresponding point of the neighboring cell, then exactly the same atomic environment will be found. And if some atom is located at one or another point of one cell, then the same atom will be located at the equivalent point of any neighboring cell. This principle is strictly valid for a perfect, ideally ordered crystal. However, many crystals (for example, metallic solid solutions) are disordered to some extent; crystallographically equivalent places can be occupied by different atoms. In these cases, it is not the position of each atom that is determined, but only the position of an atom "statistically averaged" over a large number of particles (or cells). The phenomenon of diffraction is discussed in the article OPTICS and the reader may refer to this article before moving on. It shows that if waves (for example, sound, light, X-rays) pass through a small slit or hole, then the latter can be considered as a secondary source of waves, and the image of the slit or hole consists of alternating light and dark stripes. Further, if there is a periodic structure of holes or slots, then as a result of the amplifying and attenuating interference of rays coming from different holes, a clear diffraction pattern arises. X-ray diffraction is a collective scattering phenomenon in which the role of holes and scattering centers is played by periodically arranged atoms of the crystal structure. Mutual amplification of their images at certain angles gives a diffraction pattern similar to that which would result from the diffraction of light on a three-dimensional diffraction grating. Scattering occurs due to the interaction of the incident X-ray radiation with electrons in the crystal. Due to the fact that the wavelength of X-ray radiation is of the same order as the dimensions of the atom, the wavelength of the scattered X-ray radiation is the same as that of the incident. This process is the result of forced oscillations of electrons under the action of incident X-rays. Consider now an atom with a cloud of bound electrons (surrounding the nucleus) on which X-rays are incident. Electrons in all directions simultaneously scatter the incident and emit their own X-ray radiation of the same wavelength, although of different intensity. The intensity of the scattered radiation is related to the atomic number of the element, since the atomic number is equal to the number of orbital electrons that can participate in scattering. (This dependence of the intensity on the atomic number of the scattering element and on the direction in which the intensity is measured is characterized by the atomic scattering factor, which plays an extremely important role in the analysis of the structure of crystals.) Let us choose in the crystal structure a linear chain of atoms located at the same distance from each other, and consider their diffraction pattern. It has already been noted that the X-ray spectrum consists of a continuous part ("continuum") and a set of more intense lines characteristic of the element that is the anode material. Let's say we filtered out the continuous spectrum and got an almost monochromatic X-ray beam directed at our linear chain of atoms. The amplification condition (amplifying interference) is satisfied if the difference between the paths of waves scattered by neighboring atoms is a multiple of the wavelength. If the beam is incident at an angle a0 to a line of atoms separated by intervals a (period), then for the diffraction angle a the path difference corresponding to the gain will be written as a(cos a - cosa0) = hl, where l is the wavelength and h is integer (Fig. 4 and 5).
To extend this approach to a three-dimensional crystal, it is only necessary to choose rows of atoms in two other directions in the crystal and solve the three equations thus obtained jointly for three crystal axes with periods a, b and c. The other two equations are
These are the three fundamental Laue equations for X-ray diffraction, with the numbers h, k and c being the Miller indices for the diffraction plane.
see also CRYSTALS AND CRYSTALLOGRAPHY. Considering any of the Laue equations, for example the first one, one can notice that since a, a0, l are constants, and h = 0, 1, 2, ..., its solution can be represented as a set of cones with a common axis a (Fig. . 5). The same is true for directions b and c. In the general case of three-dimensional scattering (diffraction), the three Laue equations must have a common solution, i.e. three diffraction cones located on each of the axes must intersect; the common line of intersection is shown in fig. 6. The joint solution of the equations leads to the Bragg-Wulf law:
l = 2(d/n)sinq, where d is the distance between the planes with indices h, k and c (period), n = 1, 2, ... are integers (diffraction order), and q is the angle formed by incident beam (as well as diffracting) with the plane of the crystal in which diffraction occurs. Analyzing the equation of the Bragg - Wolfe law for a single crystal located in the path of a monochromatic X-ray beam, we can conclude that diffraction is not easy to observe, because l and q are fixed, and sinq DIFFRACTION ANALYSIS METHODS
Laue method. The Laue method uses a continuous "white" spectrum of X-rays, which is directed to a stationary single crystal. For a specific value of the period d, the wavelength corresponding to the Bragg-Wulf condition is automatically selected from the entire spectrum. The Laue patterns obtained in this way make it possible to judge the directions of the diffracted beams and, consequently, the orientations of the crystal planes, which also makes it possible to draw important conclusions about the symmetry, orientation of the crystal, and the presence of defects in it. In this case, however, information about the spatial period d is lost. On fig. 7 shows an example of a Lauegram. The X-ray film was located on the side of the crystal opposite to that on which the X-ray beam was incident from the source.
Debye-Scherrer method (for polycrystalline samples). Unlike the previous method, monochromatic radiation (l = const) is used here, and the angle q is varied. This is achieved by using a polycrystalline sample consisting of numerous small crystallites of random orientation, among which there are those that satisfy the Bragg-Wulf condition. The diffracted beams form cones, the axis of which is directed along the X-ray beam. For imaging, a narrow strip of X-ray film is usually used in a cylindrical cassette, and X-rays are propagated along the diameter through holes in the film. The debyegram obtained in this way (Fig. 8) contains exact information about the period d, i.e. about the structure of the crystal, but does not give the information that the Lauegram contains. Therefore, both methods complement each other. Let us consider some applications of the Debye-Scherrer method.
Identification of chemical elements and compounds. From the angle q determined from the Debyegram, one can calculate the interplanar distance d characteristic of a given element or compound. At present, many tables of d values have been compiled, which make it possible to identify not only one or another chemical element or compound, but also various phase states of the same substance, which does not always give a chemical analysis. It is also possible to determine the content of the second component in substitutional alloys with high accuracy from the dependence of the period d on the concentration.
Stress analysis. From the measured difference in interplanar spacings for different directions in crystals, knowing the elastic modulus of the material, it is possible to calculate small stresses in it with high accuracy.
Studies of preferential orientation in crystals. If small crystallites in a polycrystalline sample are not completely randomly oriented, then the rings on the Debyegram will have different intensities. In the presence of a pronounced preferred orientation, the intensity maxima are concentrated in individual spots in the image, which becomes similar to the image for a single crystal. For example, during deep cold rolling, a metal sheet acquires a texture - a pronounced orientation of crystallites. According to the debaygram, one can judge the nature of the cold working of the material.
Study of grain sizes. If the grain size of the polycrystal is more than 10-3 cm, then the lines on the Debyegram will consist of individual spots, since in this case the number of crystallites is not enough to cover the entire range of values of the angles q. If the crystallite size is less than 10-5 cm, then the diffraction lines become wider. Their width is inversely proportional to the size of the crystallites. Broadening occurs for the same reason that a decrease in the number of slits reduces the resolution of a diffraction grating. X-ray radiation makes it possible to determine grain sizes in the range of 10-7-10-6 cm.
Methods for single crystals. In order for diffraction by a crystal to provide information not only about the spatial period, but also about the orientation of each set of diffracting planes, methods of a rotating single crystal are used. A monochromatic X-ray beam is incident on the crystal. The crystal rotates around the main axis, for which the Laue equations are satisfied. In this case, the angle q, which is included in the Bragg-Wulf formula, changes. The diffraction maxima are located at the intersection of the Laue diffraction cones with the cylindrical surface of the film (Fig. 9). The result is a diffraction pattern of the type shown in Fig. 10. However, complications are possible due to the overlap of different diffraction orders at one point. The method can be significantly improved if, simultaneously with the rotation of the crystal, the film is also moved in a certain way.
Studies of liquids and gases. It is known that liquids, gases and amorphous bodies do not have the correct crystal structure. But here, too, there is a chemical bond between the atoms in the molecules, due to which the distance between them remains almost constant, although the molecules themselves are randomly oriented in space. Such materials also give a diffraction pattern with a relatively small number of smeared maxima. The processing of such a picture by modern methods makes it possible to obtain information about the structure of even such non-crystalline materials.
SPECTROCHEMICAL X-RAY ANALYSIS
A few years after the discovery of X-rays, Ch. Barkla (1877-1944) discovered that when a high-energy X-ray flux acts on a substance, secondary fluorescent X-ray radiation is generated, which is characteristic of the element under study. Shortly thereafter, G. Moseley, in a series of his experiments, measured the wavelengths of the primary characteristic X-ray radiation obtained by electron bombardment of various elements, and deduced the relationship between the wavelength and the atomic number. These experiments, and Bragg's invention of the X-ray spectrometer, laid the foundation for spectrochemical X-ray analysis. The possibilities of X-rays for chemical analysis were immediately recognized. Spectrographs were created with registration on a photographic plate, in which the sample under study served as the anode of an X-ray tube. Unfortunately, this technique turned out to be very laborious, and therefore was used only when the usual methods of chemical analysis were inapplicable. An outstanding example of innovative research in the field of analytical X-ray spectroscopy was the discovery in 1923 by G. Hevesy and D. Coster of a new element, hafnium. The development of high-power X-ray tubes for radiography and sensitive detectors for radiochemical measurements during World War II largely contributed to the rapid growth of X-ray spectrography in the following years. This method has become widespread due to the speed, convenience, non-destructive nature of the analysis and the possibility of full or partial automation. It is applicable in the problems of quantitative and qualitative analysis of all elements with an atomic number greater than 11 (sodium). And although X-ray spectrochemical analysis is usually used to determine the most important components in a sample (from 0.1-100%), in some cases it is suitable for concentrations of 0.005% and even lower.
X-ray spectrometer. A modern X-ray spectrometer consists of three main systems (Fig. 11): excitation systems, i.e. x-ray tube with an anode made of tungsten or other refractory material and a power supply; analysis systems, i.e. an analyzer crystal with two multi-slit collimators, as well as a spectrogoniometer for fine adjustment; and registration systems with a Geiger or proportional or scintillation counter, as well as a rectifier, amplifier, counters and a chart recorder or other recording device.
X-ray fluorescent analysis. The analyzed sample is located in the path of the exciting x-rays. The region of the sample to be examined is usually isolated by a mask with a hole of the desired diameter, and the radiation passes through a collimator that forms a parallel beam. Behind the analyzer crystal, a slit collimator emits diffracted radiation for the detector. Usually, the maximum angle q is limited to 80–85°, so that only X-rays whose wavelength l is related to the interplanar distance d by the inequality l can diffract on the analyzer crystal. X-ray microanalysis. The flat analyzer crystal spectrometer described above can be adapted for microanalysis. This is achieved by constricting either the primary x-ray beam or the secondary beam emitted by the sample. However, a decrease in the effective size of the sample or the radiation aperture leads to a decrease in the intensity of the recorded diffracted radiation. An improvement to this method can be achieved by using a curved crystal spectrometer, which makes it possible to register a cone of divergent radiation, and not only radiation parallel to the axis of the collimator. With such a spectrometer, particles smaller than 25 µm can be identified. An even greater reduction in the size of the analyzed sample is achieved in the X-ray electron probe microanalyzer invented by R. Kasten. Here, a highly focused electron beam excites the characteristic X-ray emission of the sample, which is then analyzed by a bent-crystal spectrometer. Using such a device, it is possible to detect amounts of a substance of the order of 10–14 g in a sample with a diameter of 1 μm. Installations with electron beam scanning of the sample have also been developed, with the help of which it is possible to obtain a two-dimensional pattern of the distribution over the sample of the element whose characteristic radiation is tuned to the spectrometer.
MEDICAL X-RAY DIAGNOSIS
The development of x-ray technology has significantly reduced the exposure time and improved the quality of images, allowing even soft tissues to be studied.
Fluorography. This diagnostic method consists in photographing a shadow image from a translucent screen. The patient is placed between an x-ray source and a flat screen of phosphor (usually cesium iodide), which glows when exposed to x-rays. Biological tissues of varying degrees of density create shadows of X-ray radiation with varying degrees of intensity. A radiologist examines a shadow image on a fluorescent screen and makes a diagnosis. In the past, a radiologist relied on vision to analyze an image. Now there are various systems that amplify the image, display it on a television screen or record data in the computer's memory.
Radiography. The recording of an x-ray image directly on photographic film is called radiography. In this case, the organ under study is located between the X-ray source and the film, which captures information about the state of the organ at a given time. Repeated radiography makes it possible to judge its further evolution. Radiography allows you to very accurately examine the integrity of bone tissue, which consists mainly of calcium and is opaque to x-rays, as well as muscle tissue ruptures. With its help, better than a stethoscope or listening, the condition of the lungs is analyzed in case of inflammation, tuberculosis, or the presence of fluid. With the help of radiography, the size and shape of the heart, as well as the dynamics of its changes in patients suffering from heart disease, are determined.
contrast agents. Parts of the body and cavities of individual organs that are transparent to X-ray radiation become visible if they are filled with a contrast agent that is harmless to the body, but allows one to visualize the shape of internal organs and check their functioning. The patient either takes contrast agents orally (such as barium salts in the study of the gastrointestinal tract), or they are administered intravenously (such as iodine-containing solutions in the study of the kidneys and urinary tract). In recent years, however, these methods have been supplanted by diagnostic methods based on the use of radioactive atoms and ultrasound.
CT scan. In the 1970s, a new method of X-ray diagnostics was developed, based on a complete photograph of the body or its parts. Images of thin layers ("slices") are processed by a computer, and the final image is displayed on the monitor screen. This method is called computed x-ray tomography. It is widely used in modern medicine for diagnosing infiltrates, tumors and other brain disorders, as well as for diagnosing diseases of soft tissues inside the body. This technique does not require the introduction of foreign contrast agents and is therefore faster and more effective than traditional techniques.
BIOLOGICAL ACTION OF X-RAY RADIATION
The harmful biological effect of X-ray radiation was discovered shortly after its discovery by Roentgen. It turned out that the new radiation can cause something like a severe sunburn (erythema), accompanied, however, by deeper and more permanent damage to the skin. Appearing ulcers often turned into cancer. In many cases, fingers or hands had to be amputated. There were also deaths. It has been found that skin damage can be avoided by reducing exposure time and dose, using shielding (eg lead) and remote controls. But gradually other, more long-term effects of X-ray exposure were revealed, which were then confirmed and studied in experimental animals. The effects due to the action of X-rays, as well as other ionizing radiations (such as gamma radiation emitted by radioactive materials) include: 1) temporary changes in the composition of the blood after a relatively small excess exposure; 2) irreversible changes in the composition of the blood (hemolytic anemia) after prolonged excessive exposure; 3) an increase in the incidence of cancer (including leukemia); 4) faster aging and early death; 5) the occurrence of cataracts. In addition, biological experiments on mice, rabbits and flies (Drosophila) have shown that even small doses of systematic irradiation of large populations, due to an increase in the rate of mutation, lead to harmful genetic effects. Most geneticists recognize the applicability of these data to the human body. As for the biological effect of X-ray radiation on the human body, it is determined by the level of the radiation dose, as well as by which particular organ of the body was exposed to radiation. For example, blood diseases are caused by irradiation of blood-forming organs, mainly bone marrow, and genetic consequences - by irradiation of the genital organs, which can also lead to sterility. The accumulation of knowledge about the effects of X-ray radiation on the human body has led to the development of national and international standards for permissible radiation doses, published in various reference publications. In addition to X-rays, which are purposefully used by humans, there is also the so-called scattered, side radiation that occurs for various reasons, for example, due to scattering due to the imperfection of the lead protective screen, which does not completely absorb this radiation. In addition, many electrical devices that are not designed to produce X-rays nevertheless generate X-rays as a by-product. Such devices include electron microscopes, high-voltage rectifier lamps (kenotrons), as well as kinescopes of outdated color televisions. The production of modern color kinescopes in many countries is now under government control.
HAZARDOUS FACTORS OF X-RAY RADIATION
The types and degree of danger of X-ray exposure for people depend on the contingent of people exposed to radiation.
Professionals working with x-ray equipment. This category includes radiologists, dentists, as well as scientific and technical workers and personnel maintaining and using x-ray equipment. Effective measures are being taken to reduce the levels of radiation they have to deal with.
Patients. There are no strict criteria here, and the safe level of radiation that patients receive during treatment is determined by the attending physicians. Physicians are advised not to unnecessarily expose patients to x-rays. Particular caution should be exercised when examining pregnant women and children. In this case, special measures are taken.
Control methods. There are three aspects to this:
1) availability of adequate equipment, 2) enforcement of safety regulations, 3) proper use of equipment. In an x-ray examination, only the desired area should be exposed to radiation, be it dental examinations or lung examinations. Note that immediately after turning off the X-ray apparatus, both primary and secondary radiation disappear; there is also no residual radiation, which is not always known even to those who are directly connected with it in their work.
see also
ATOM STRUCTURE;
Radiology is a section of radiology that studies the effects of X-ray radiation on the body of animals and humans arising from this disease, their treatment and prevention, as well as methods for diagnosing various pathologies using X-rays (X-ray diagnostics). A typical X-ray diagnostic apparatus includes a power supply (transformers), a high-voltage rectifier that converts the alternating current of the electrical network into direct current, a control panel, a tripod and an X-ray tube.
X-rays are a type of electromagnetic oscillations that are formed in an X-ray tube during a sharp deceleration of accelerated electrons at the moment of their collision with the atoms of the anode substance. At present, the point of view is generally accepted that X-rays, by their physical nature, are one of the types of radiant energy, the spectrum of which also includes radio waves, infrared rays, visible light, ultraviolet rays and gamma rays of radioactive elements. X-ray radiation can be characterized as a collection of its smallest particles - quanta or photons.
Rice. 1 - mobile x-ray machine:
A - x-ray tube;
B - power supply;
B - adjustable tripod.
Rice. 2 - X-ray machine control panel (mechanical - on the left and electronic - on the right): A - panel for adjusting exposure and hardness;
B - high voltage supply button.
Rice. 3 is a block diagram of a typical x-ray machine 1 - network;
2 - autotransformer;
3 - step-up transformer;
4 - x-ray tube;
5 - anode;
6 - cathode;
7 - step-down transformer.
Mechanism of X-ray generation
X-rays are formed at the moment of collision of a stream of accelerated electrons with the anode material. When electrons interact with a target, 99% of their kinetic energy is converted into thermal energy and only 1% into X-rays.
An X-ray tube consists of a glass container in which 2 electrodes are soldered: a cathode and an anode. Air is pumped out of the glass cylinder: the movement of electrons from the cathode to the anode is possible only under conditions of relative vacuum (10 -7 -10 -8 mm Hg). On the cathode there is a filament, which is a tightly twisted tungsten filament. When an electric current is applied to the filament, electron emission occurs, in which electrons are separated from the spiral and form an electron cloud near the cathode. This cloud is concentrated at the focusing cup of the cathode, which sets the direction of electron movement. Cup - a small depression in the cathode. The anode, in turn, contains a tungsten metal plate on which the electrons are focused - this is the site of the formation of x-rays.
Rice. 4 - X-ray tube device: A - cathode; 
B - anode;
B - tungsten filament;
G - focusing cup of the cathode;
D - stream of accelerated electrons;
E - tungsten target;
G - glass flask;
З - a window from beryllium;
And - formed x-rays;
K - aluminum filter.
2 transformers are connected to the electron tube: step-down and step-up. A step-down transformer heats the tungsten filament with a low voltage (5-15 volts), resulting in electron emission. A step-up, or high-voltage, transformer goes directly to the cathode and anode, which are supplied with a voltage of 20–140 kilovolts. Both transformers are placed in the high-voltage block of the X-ray machine, which is filled with transformer oil, which provides cooling of the transformers and their reliable insulation.
After an electron cloud has formed with the help of a step-down transformer, the step-up transformer is turned on, and high-voltage voltage is applied to both poles of the electrical circuit: a positive pulse to the anode, and a negative pulse to the cathode. Negatively charged electrons are repelled from a negatively charged cathode and tend to a positively charged anode - due to such a potential difference, a high speed of movement is achieved - 100 thousand km / s. At this speed, electrons bombard the tungsten anode plate, completing an electrical circuit, resulting in X-rays and thermal energy.
X-ray radiation is subdivided into bremsstrahlung and characteristic. Bremsstrahlung occurs due to a sharp deceleration of the speed of electrons emitted by a tungsten filament. Characteristic radiation occurs at the moment of rearrangement of the electron shells of atoms. Both of these types are formed in an X-ray tube at the moment of collision of accelerated electrons with atoms of the anode material. The emission spectrum of an X-ray tube is a superposition of bremsstrahlung and characteristic X-rays.
Rice. 5 - the principle of the formation of bremsstrahlung X-rays.
Rice. 6 - the principle of formation of the characteristic x-ray radiation.
Basic properties of X-rays
- X-rays are invisible to visual perception.
- X-ray radiation has a great penetrating power through the organs and tissues of a living organism, as well as dense structures of inanimate nature, which do not transmit visible light rays.
- X-rays cause certain chemical compounds to glow, called fluorescence.
- Zinc and cadmium sulfides fluoresce yellow-green,
- Crystals of calcium tungstate - violet-blue.
Scale of electromagnetic oscillations
X-rays have a specific wavelength and frequency of oscillation. Wavelength (λ) and oscillation frequency (ν) are related by the relationship: λ ν = c, where c is the speed of light, rounded to 300,000 km per second. The energy of X-rays is determined by the formula E = h ν, where h is Planck's constant, a universal constant equal to 6.626 10 -34 J⋅s. The wavelength of the rays (λ) is related to their energy (E) by the relation: λ = 12.4 / E.
X-ray radiation differs from other types of electromagnetic oscillations in wavelength (see table) and quantum energy. The shorter the wavelength, the higher its frequency, energy and penetrating power. The X-ray wavelength is in the range
. By changing the wavelength of X-ray radiation, it is possible to control its penetrating power. X-rays have a very short wavelength, but a high frequency of oscillation, so they are invisible to the human eye. Due to their enormous energy, quanta have a high penetrating power, which is one of the main properties that ensure the use of X-rays in medicine and other sciences.X-ray characteristics
Intensity- quantitative characteristic of x-ray radiation, which is expressed by the number of rays emitted by the tube per unit time. The intensity of X-rays is measured in milliamps. Comparing it with the intensity of visible light from a conventional incandescent lamp, we can draw an analogy: for example, a 20-watt lamp will shine with one intensity, or power, and a 200-watt lamp will shine with another, while the quality of the light itself (its spectrum) is the same . The intensity of X-ray radiation is, in fact, its quantity. Each electron creates one or more radiation quanta on the anode, therefore, the amount of X-rays during exposure of the object is regulated by changing the number of electrons tending to the anode and the number of interactions of electrons with atoms of the tungsten target, which can be done in two ways:
- By changing the degree of incandescence of the cathode spiral using a step-down transformer (the number of electrons generated during emission will depend on how hot the tungsten spiral is, and the number of radiation quanta will depend on the number of electrons);
- By changing the value of the high voltage supplied by the step-up transformer to the poles of the tube - the cathode and the anode (the higher the voltage is applied to the poles of the tube, the more kinetic energy the electrons receive, which, due to their energy, can interact with several atoms of the anode substance in turn - see Fig. rice. 5; electrons with low energy will be able to enter into a smaller number of interactions).
The X-ray intensity (anode current) multiplied by the exposure (tube time) corresponds to the X-ray exposure, which is measured in mAs (milliamps per second). Exposure is a parameter that, like intensity, characterizes the amount of rays emitted by an x-ray tube. The only difference is that the exposure also takes into account the operating time of the tube (for example, if the tube works for 0.01 sec, then the number of rays will be one, and if 0.02 sec, then the number of rays will be different - twice more). The radiation exposure is set by the radiologist on the control panel of the X-ray machine, depending on the type of examination, the size of the object under study and the diagnostic task.
Rigidity- qualitative characteristic of x-ray radiation. It is measured by the high voltage on the tube - in kilovolts. Determines the penetrating power of x-rays. It is regulated by the high voltage supplied to the X-ray tube by a step-up transformer. The higher the potential difference is created on the electrodes of the tube, the more force the electrons repel from the cathode and rush to the anode, and the stronger their collision with the anode. The stronger their collision, the shorter the wavelength of the resulting X-ray radiation and the higher the penetrating power of this wave (or the hardness of the radiation, which, like the intensity, is regulated on the control panel by the voltage parameter on the tube - kilovoltage).
λ - wavelength; 
Rice. 7 - Dependence of the wavelength on the energy of the wave:
E - wave energy 
Rice. 8 - The ratio of the voltage on the X-ray tube and the wavelength of the resulting X-ray radiation:
Classification of x-ray tubes
- By appointment
- Diagnostic
- Therapeutic
- For structural analysis
- For transillumination
- By design
- By focus
- Single-focus (one spiral on the cathode, and one focal spot on the anode)
- Bifocal (two spirals of different sizes on the cathode, and two focal spots on the anode)
- By type of anode
- Stationary (fixed)
- Rotating
X-rays are used not only for radiodiagnostic purposes, but also for therapeutic purposes. As noted above, the ability of X-ray radiation to suppress the growth of tumor cells makes it possible to use it in radiation therapy of oncological diseases. In addition to the medical field of application, X-ray radiation has found wide application in the engineering and technical field, materials science, crystallography, chemistry and biochemistry: for example, it is possible to identify structural defects in various products (rails, welds, etc.) using X-ray radiation. The type of such research is called defectoscopy. And at airports, railway stations and other crowded places, X-ray television introscopes are actively used to scan hand luggage and baggage for security purposes.
Depending on the type of anode, X-ray tubes differ in design. Due to the fact that 99% of the kinetic energy of the electrons is converted into thermal energy, during the operation of the tube, the anode is significantly heated - the sensitive tungsten target often burns out. The anode is cooled in modern X-ray tubes by rotating it. The rotating anode has the shape of a disk, which distributes heat evenly over its entire surface, preventing local overheating of the tungsten target.
The design of X-ray tubes also differs in focus. Focal spot - the section of the anode on which the working X-ray beam is generated. It is subdivided into the real focal spot and the effective focal spot ( rice. 12). Due to the angle of the anode, the effective focal spot is smaller than the real one. Different focal spot sizes are used depending on the size of the image area. The larger the image area, the wider the focal spot must be to cover the entire image area. However, a smaller focal spot produces better image clarity. Therefore, when producing small images, a short filament is used and the electrons are directed to a small area of the anode target, creating a smaller focal spot.
Rice. 9 - x-ray tube with a stationary anode.
Rice. 10 - X-ray tube with a rotating anode.
Rice. 11 - X-ray tube device with a rotating anode.
Rice. 12 is a diagram of the formation of a real and effective focal spot.
LECTURE
X-RAY RADIATION
2. Bremsstrahlung X-ray, its spectral properties.
3. Characteristic x-ray radiation (for review).
4. Interaction of X-ray radiation with matter.
5.Physical basis for the use of X-rays in medicine.
X-rays (X - rays) were discovered by K. Roentgen, who in 1895 became the first Nobel laureate in physics.
1. The nature of X-rays
x-ray radiation - electromagnetic waves with a length of 80 to 10 -5 nm. Long-wave X-ray radiation is blocked by short-wave UV radiation, short-wave - by long-wave g-radiation.
X-rays are produced in x-ray tubes. fig.1.
K - cathode
1 - electron beam
2 - X-ray radiation
Rice. 1. X-ray tube device.
The tube is a glass flask (with a possible high vacuum: the pressure in it is about 10 -6 mm Hg) with two electrodes: anode A and cathode K, to which a high voltage is applied
U (several thousand volts). The cathode is a source of electrons (due to the phenomenon of thermionic emission). The anode is a metal rod that has an inclined surface in order to direct the resulting X-ray radiation at an angle to the axis of the tube. It is made of a highly heat-conducting material to remove the heat generated during electron bombardment. On the beveled end there is a plate made of refractory metal (for example, tungsten).The strong heating of the anode is due to the fact that the main number of electrons in the cathode beam, having hit the anode, experience numerous collisions with the atoms of the substance and transfer a large amount of energy to them.
Under the action of high voltage, the electrons emitted by the hot cathode filament are accelerated to high energies. The kinetic energy of an electron is
mv 2 /2. It is equal to the energy that it acquires by moving in the electrostatic field of the tube:mv 2 /2 = eU(1)
where m , e are the mass and charge of the electron, U is the accelerating voltage.
The processes leading to the appearance of bremsstrahlung X-rays are due to the intense deceleration of electrons in the anode material by the electrostatic field of the atomic nucleus and atomic electrons.
The origin mechanism can be represented as follows. Moving electrons are some kind of current that forms its own magnetic field. Electron deceleration is a decrease in the current strength and, accordingly, a change in the magnetic field induction, which will cause the appearance of an alternating electric field, i.e. appearance of an electromagnetic wave.
Thus, when a charged particle flies into matter, it slows down, loses its energy and speed, and emits electromagnetic waves.
2. Spectral properties of X-ray bremsstrahlung .
So, in the case of electron deceleration in the anode material, bremsstrahlung radiation.
The bremsstrahlung spectrum is continuous . The reason for this is as follows.
When the electrons slow down, each of them has a part of the energy used to heat the anode (E 1 =
Q ), the other part to create an X-ray photon (E 2 = hv ), otherwise, eU = hv + Q . The relationship between these parts is random.Thus, a continuous spectrum of bremsstrahlung X-rays is formed due to the deceleration of many electrons, each of which emits one X-ray quantum
hv(h ) of a strictly defined value. The value of this quantum different for different electrons. Dependence of the X-ray energy flux on the wavelength l , i.e. the X-ray spectrum is shown in Fig.2. |
Fig.2. Bremsstrahlung spectrum: a) at different voltages
U in the tube; b) at different temperatures T of the cathode.Short-wave (hard) radiation has a greater penetrating power than long-wave (soft) radiation. Soft radiation is more strongly absorbed by matter.
From the side of short wavelengths, the spectrum ends abruptly at a certain wavelength
l m i n . Such short-wavelength bremsstrahlung occurs when the energy acquired by an electron in an accelerating field is completely converted into photon energy ( Q = 0):eU = hv max = hc/ l min , l min = hc/(eU), (2)
l min (nm) = 1.23 / U kV
The spectral composition of the radiation depends on the voltage on the X-ray tube, with increasing voltage, the value
l m i n shifts towards short wavelengths (Fig. 2 a).When the temperature T of the cathode incandescence changes, the electron emission increases. Therefore, the current increases
I in the tube, but the spectral composition of the radiation does not change (Fig. 2b).Energy flow Ф * bremsstrahlung is directly proportional to the square of the voltage U between anode and cathode, current strength I in tube and atomic number Z anode materials:
F \u003d kZU 2 I. (3)
where k \u003d 10 -9 W / (V 2 A).
3. Characteristic X-rays (for familiarization).
Increasing the voltage on the X-ray tube leads to the fact that against the background of a continuous spectrum, a line appears, which corresponds to the characteristic X-ray radiation. This radiation is specific to the anode material.
The mechanism of its occurrence is as follows. At a high voltage, accelerated electrons (with high energy) penetrate deep into the atom and knock electrons out of its inner layers. Electrons from upper levels pass to free places, as a result of which photons of characteristic radiation are emitted.
The spectra of characteristic X-ray radiation differ from optical spectra.
- Uniformity.
The uniformity of the characteristic spectra is due to the fact that the internal electron layers of different atoms are the same and differ only energetically due to the force effect from the nuclei, which increases with increasing elemental number. Therefore, the characteristic spectra shift towards higher frequencies with increasing nuclear charge. This was experimentally confirmed by an employee of Roentgen - Moseley, who measured X-ray transition frequencies for 33 elements. They made the law.
MOSELY'S LAW – the square root of the frequency of the characteristic radiation is a linear function of the ordinal number of the element:
A × (Z – B ), (4)
where v is the spectral line frequency, Z is the atomic number of the emitting element. A, B are constants.
The importance of Moseley's law lies in the fact that this dependence can be used to accurately determine the atomic number of the element under study from the measured frequency of the X-ray line. This played a big role in the placement of the elements in the periodic table.
– Independence from a chemical compound.
The characteristic X-ray spectra of an atom do not depend on the chemical compound in which the atom of the element enters. For example, the X-ray spectrum of an oxygen atom is the same for O 2, H 2 O, while the optical spectra of these compounds differ. This feature of the x-ray spectrum of the atom was the basis for the name " characteristic radiation".
4. Interaction of X-ray radiation with matter
The impact of X-ray radiation on objects is determined by the primary processes of X-ray interaction. photon with electrons atoms and molecules of matter.
X-ray radiation in matter absorbed or dissipates. In this case, various processes can occur, which are determined by the ratio of the X-ray photon energy
hv and ionization energy A and (ionization energy A and - the energy required to remove internal electrons from the atom or molecule).a) Coherent scattering(scattering of long-wave radiation) occurs when the relation
hv< А и.
For photons, due to interaction with electrons, only the direction of movement changes (Fig. 3a), but the energy
hv and the wavelength do not change (hence this scattering is called coherent). Since the energies of a photon and an atom do not change, coherent scattering does not affect biological objects, but when creating protection against X-ray radiation, one should take into account the possibility of changing the primary direction of the beam.b) photoelectric effect happens when
hv ³ A and .
In this case, two cases can be realized.
1. The photon is absorbed, the electron is detached from the atom (Fig. 3b). Ionization occurs. The detached electron acquires kinetic energy: E k \u003d hv - A and . If the kinetic energy is large, then the electron can ionize neighboring atoms by collision, forming new ones. secondary electrons.
2. The photon is absorbed, but its energy is not enough to detach the electron, and excitation of an atom or molecule(Fig. 3c). This often leads to the subsequent emission of a photon in the visible radiation region (X-ray luminescence), and in tissues - to the activation of molecules and photochemical reactions. The photoelectric effect occurs mainly on the electrons of the inner shells of atoms with high Z.
in) Incoherent scattering(Compton effect, 1922) occurs when the photon energy is much greater than the ionization energy
hv » A and.
In this case, the electron is detached from the atom (such electrons are called recoil electrons), acquires some kinetic energy
E to , the energy of the photon itself decreases (Fig. 4d):hv=hv" + A and + E k. (5)
The resulting radiation with a changed frequency (length) is called secondary, it scatters in all directions.
Recoil electrons, if they have sufficient kinetic energy, can ionize neighboring atoms by collision. Thus, as a result of incoherent scattering, secondary scattered X-ray radiation is formed and the atoms of the substance are ionized.
These (a, b, c) processes can cause a number of subsequent ones. For example (Fig. 3d), if during the photoelectric effect electrons are detached from the atom on the inner shells, then electrons from higher levels can pass in their place, which is accompanied by secondary characteristic x-ray radiation of this substance. Photons of secondary radiation, interacting with electrons of neighboring atoms, can, in turn, cause secondary phenomena.
coherent scattering
hv< А И
| |
photoelectric effect
photon is absorbed, e - detached from the atom - ionization
hv \u003d A and + E to
atom A excited by the absorption of a photon, R – X-ray luminescence
incoherent scattering
hv » A and
hv \u003d hv "+ A and + E to
secondary processes in the photoelectric effect
 |
Rice. 3 Mechanisms of interaction of X-rays with matter
Physical basis for the use of X-rays in medicine
When X-rays fall on a body, it is slightly reflected from its surface, but mainly passes deep into, while it is partially absorbed and scattered, and partially passes through.
The law of weakening.
The X-ray flux is attenuated in matter according to the law:
F \u003d F 0 e - m × x (6)
where m – linear attenuation factor, which essentially depends on the density of the substance. It is equal to the sum of three terms corresponding to coherent scattering m 1, incoherent m 2 and photoelectric effect m 3:
m \u003d m 1 + m 2 + m 3. (7)
The contribution of each term is determined by the photon energy. Below are the ratios of these processes for soft tissues (water).
Energy, keV | photoelectric effect | Compton - effect |
| 100 % |
enjoy mass attenuation coefficient, which does not depend on the density of the substance r :
m m = m / r . (eight)
The mass attenuation coefficient depends on the energy of the photon and on the atomic number of the absorbing substance:
m m = k l 3 Z 3 . (nine)
Mass attenuation coefficients of bone and soft tissue (water) differ: m m bones / m m water = 68.
If an inhomogeneous body is placed in the path of X-rays and a fluorescent screen is placed in front of it, then this body, absorbing and attenuating the radiation, forms a shadow on the screen. By the nature of this shadow, one can judge the shape, density, structure, and in many cases the nature of bodies. Those. a significant difference in the absorption of x-ray radiation by different tissues allows you to see the image of the internal organs in the shadow projection.
If the organ under study and the surrounding tissues equally attenuate x-rays, then contrast agents are used. So, for example, filling the stomach and intestines with a mushy mass of barium sulfate ( BaS 0 4), you can see their shadow image (the ratio of attenuation coefficients is 354).
Use in medicine.
In medicine, X-ray radiation with photon energy from 60 to 100-120 keV is used for diagnostics and 150-200 keV for therapy.
X-ray diagnostics – Recognition of diseases by transilluminating the body with X-rays.
X-ray diagnostics is used in various options, which are given below.
 |
1. With fluoroscopy the x-ray tube is located behind the patient. In front of it is a fluorescent screen. There is a shadow (positive) image on the screen. In each individual case, the appropriate hardness of the radiation is selected so that it passes through soft tissues, but is sufficiently absorbed by dense ones. Otherwise, a uniform shadow is obtained. On the screen, the heart, the ribs are visible dark, the lungs are light.
2. When radiography the object is placed on a cassette, which contains a film with a special photographic emulsion. The X-ray tube is placed over the object. The resulting radiograph gives a negative image, i.e. the opposite in contrast to the picture observed during transillumination. In this method, there is a greater clarity of the image than in (1), therefore, details are observed that are difficult to see when transilluminated.
A promising variant of this method is X-ray tomography and "machine version" - computer tomography.
3. With fluoroscopy, On a sensitive small-format film, the image from the large screen is fixed. When viewed, the pictures are examined on a special magnifier.
X-ray therapy - the use of X-rays to destroy malignant tumors.
The biological effect of radiation is to disrupt vital activity, especially rapidly multiplying cells.
COMPUTED TOMOGRAPHY (CT)
The method of X-ray computed tomography is based on image reconstructionof a certain section of the patient's body by registering a large number of X-ray projections of this section, made at different angles. Information from the sensors that register these projections enters the computer, which, according to a special program calculates distribution tight sample sizein the investigated section and displays it on the display screen. The resulting imagesection of the patient's body is characterized by excellent clarity and high information content. The program allows you toincrease image contrast in dozens and even hundreds of times. This expands the diagnostic capabilities of the method.
Videographers (devices with digital X-ray image processing) in modern dentistry.
In dentistry, X-ray examination is the main diagnostic method. However, a number of traditional organizational and technical features of X-ray diagnostics make it not quite comfortable for both the patient and dental clinics. This is, first of all, the need for the patient to come into contact with ionizing radiation, which often creates a significant radiation load on the body, it is also the need for a photoprocess, and, consequently, the need for photoreagents, including toxic ones. This is, finally, a bulky archive, heavy folders and envelopes with x-ray films.
In addition, the current level of development of dentistry makes the subjective assessment of radiographs by the human eye insufficient. As it turned out, of the variety of shades of gray contained in the x-ray image, the eye perceives only 64.
Obviously, to obtain a clear and detailed image of the hard tissues of the dentoalveolar system with minimal radiation exposure, other solutions are needed. The search led to the creation of so-called radiographic systems, videographers - digital radiography systems.
Without technical details, the principle of operation of such systems is as follows. X-ray radiation enters through the object not on a photosensitive film, but on a special intraoral sensor (special electronic matrix). The corresponding signal from the matrix is transmitted to a digitizing device (analog-to-digital converter, ADC) that converts it into digital form and is connected to the computer. Special software builds an x-ray image on the computer screen and allows you to process it, save it on a hard or flexible storage medium (hard drive, floppy disks), print it as a picture as a file.
In a digital system, an x-ray image is a collection of dots having different digital grayscale values. The information display optimization provided by the program makes it possible to obtain an optimal frame in terms of brightness and contrast at a relatively low radiation dose.
In modern systems created, for example, by firms Trophy (France) or Schick (USA) when forming a frame, 4096 shades of gray are used, the exposure time depends on the object of study and, on average, is hundredths - tenths of a second, reduction of radiation exposure in relation to the film - up to 90% for intraoral systems, up to 70% for panoramic videographers.
When processing images, videographers allow:
1. Get positive and negative images, false color images, embossed images.
2. Increase contrast and magnify the area of interest in the image.
3. Assess changes in the density of dental tissues and bone structures, control the uniformity of canal filling.
4. In endodontics to determine the length of the channel of any curvature, and in surgery to select the size of the implant with an accuracy of 0.1 mm.
5. Unique system caries detector with elements of artificial intelligence in the analysis of the picture allows you to detect caries in the stain stage, root caries and hidden caries.
* « Ф" in formula (3) refers to the entire range of emitted wavelengths and is often referred to as "Integral Energy Flux".
X-rays are a type of high-energy electromagnetic radiation. It is actively used in various branches of medicine.
X-rays are electromagnetic waves whose photon energy on the scale of electromagnetic waves is between ultraviolet radiation and gamma radiation (from ~10 eV to ~1 MeV), which corresponds to wavelengths from ~10^3 to ~10^−2 angstroms ( from ~10^−7 to ~10^−12 m). That is, it is incomparably harder radiation than visible light, which is on this scale between ultraviolet and infrared ("thermal") rays.
The boundary between X-rays and gamma radiation is distinguished conditionally: their ranges intersect, gamma rays can have an energy of 1 keV. They differ in origin: gamma rays are emitted during processes occurring in atomic nuclei, while X-rays are emitted during processes involving electrons (both free and those in the electron shells of atoms). At the same time, it is impossible to determine from the photon itself during which process it arose, that is, the division into the X-ray and gamma ranges is largely arbitrary.
The x-ray range is divided into "soft x-ray" and "hard". The boundary between them lies at the wavelength level of 2 angstroms and 6 keV of energy.
The X-ray generator is a tube in which a vacuum is created. There are electrodes - a cathode, to which a negative charge is applied, and a positively charged anode. The voltage between them is tens to hundreds of kilovolts. The generation of X-ray photons occurs when electrons “break off” from the cathode and crash into the anode surface at high speed. The resulting X-ray radiation is called "bremsstrahlung", its photons have different wavelengths.
At the same time, photons of the characteristic spectrum are generated. Part of the electrons in the atoms of the anode substance is excited, that is, it goes to higher orbits, and then returns to its normal state, emitting photons of a certain wavelength. Both types of X-rays are produced in a standard generator.
Discovery history
On November 8, 1895, the German scientist Wilhelm Conrad Roentgen discovered that some substances under the influence of "cathode rays", that is, the flow of electrons generated by a cathode ray tube, begin to glow. He explained this phenomenon by the influence of certain X-rays - so (“X-rays”) this radiation is now called in many languages. Later V.K. Roentgen studied the phenomenon he had discovered. On December 22, 1895, he gave a lecture on this topic at the University of Würzburg.
Later it turned out that X-ray radiation had been observed before, but then the phenomena associated with it were not given much importance. The cathode ray tube was invented a long time ago, but before V.K. X-ray, no one paid much attention to the blackening of photographic plates near it, etc. phenomena. The danger posed by penetrating radiation was also unknown.
Types and their effect on the body
"X-ray" is the mildest type of penetrating radiation. Overexposure to soft x-rays is similar to ultraviolet exposure, but in a more severe form. A burn forms on the skin, but the lesion is deeper, and it heals much more slowly.
Hard X-ray is a full-fledged ionizing radiation that can lead to radiation sickness. X-ray quanta can break the protein molecules that make up the tissues of the human body, as well as the DNA molecules of the genome. But even if an X-ray quantum breaks a water molecule, it doesn't matter: in this case, chemically active free radicals H and OH are formed, which themselves are able to act on proteins and DNA. Radiation sickness proceeds in a more severe form, the more the hematopoietic organs are affected.
X-rays have mutagenic and carcinogenic activity. This means that the probability of spontaneous mutations in cells during irradiation increases, and sometimes healthy cells can degenerate into cancerous ones. Increasing the likelihood of malignant tumors is a standard consequence of any exposure, including x-rays. X-rays are the least dangerous type of penetrating radiation, but they can still be dangerous.
X-ray radiation: application and how it works
X-ray radiation is used in medicine, as well as in other areas of human activity.
Fluoroscopy and computed tomography
The most common use of X-rays is fluoroscopy. "Silence" of the human body allows you to get a detailed image of both the bones (they are most clearly visible) and images of the internal organs.
Different transparency of body tissues in x-rays is associated with their chemical composition. Features of the structure of bones is that they contain a lot of calcium and phosphorus. Other tissues are composed mainly of carbon, hydrogen, oxygen and nitrogen. The phosphorus atom is almost twice as heavy as the oxygen atom, and the calcium atom is 2.5 times (carbon, nitrogen and hydrogen are even lighter than oxygen). In this regard, the absorption of X-ray photons in the bones is much higher.
In addition to two-dimensional "pictures", radiography makes it possible to create a three-dimensional image of an organ: this type of radiography is called computed tomography. For these purposes, soft x-rays are used. The amount of exposure received in a single image is small: it is approximately equal to the exposure received during a 2-hour flight in an airplane at an altitude of 10 km.
X-ray flaw detection allows you to detect small internal defects in products. Hard x-rays are used for it, since many materials (metal, for example) are poorly “translucent” due to the high atomic mass of their constituent substance.
X-ray diffraction and X-ray fluorescence analysis
X-rays have properties that allow them to examine individual atoms in detail. X-ray diffraction analysis is actively used in chemistry (including biochemistry) and crystallography. The principle of its operation is the diffraction scattering of X-rays by atoms of crystals or complex molecules. Using X-ray diffraction analysis, the structure of the DNA molecule was determined.
X-ray fluorescence analysis allows you to quickly determine the chemical composition of a substance.
There are many forms of radiotherapy, but they all involve the use of ionizing radiation. Radiotherapy is divided into 2 types: corpuscular and wave. Corpuscular uses flows of alpha particles (nuclei of helium atoms), beta particles (electrons), neutrons, protons, heavy ions. Wave uses rays of the electromagnetic spectrum - x-rays and gamma.
Radiotherapy methods are used primarily for the treatment of oncological diseases. The fact is that radiation primarily affects actively dividing cells, which is why the hematopoietic organs suffer this way (their cells are constantly dividing, producing more and more new red blood cells). Cancer cells are also constantly dividing and are more vulnerable to radiation than healthy tissue.
A level of radiation is used that suppresses the activity of cancer cells, while moderately affecting healthy ones. Under the influence of radiation, it is not the destruction of cells as such, but the damage to their genome - DNA molecules. A cell with a destroyed genome may exist for some time, but can no longer divide, that is, tumor growth stops.
Radiation therapy is the mildest form of radiotherapy. Wave radiation is softer than corpuscular radiation, and X-rays are softer than gamma radiation.
During pregnancy
It is dangerous to use ionizing radiation during pregnancy. X-rays are mutagenic and can cause abnormalities in the fetus. X-ray therapy is incompatible with pregnancy: it can only be used if it has already been decided to have an abortion. Restrictions on fluoroscopy are softer, but in the first months it is also strictly prohibited.
In case of emergency, X-ray examination is replaced by magnetic resonance imaging. But in the first trimester they try to avoid it too (this method has appeared recently, and with absolute certainty to speak about the absence of harmful consequences).
An unequivocal danger arises when exposed to a total dose of at least 1 mSv (in old units - 100 mR). With a simple x-ray (for example, when undergoing fluorography), the patient receives about 50 times less. In order to receive such a dose at a time, you need to undergo a detailed computed tomography.
That is, the mere fact of a 1-2-fold “X-ray” at an early stage of pregnancy does not threaten with serious consequences (but it’s better not to risk it).
Treatment with it
X-rays are used primarily in the fight against malignant tumors. This method is good because it is highly effective: it kills the tumor. It is bad because healthy tissues have a little better, there are numerous side effects. The organs of hematopoiesis are at particular risk.
In practice, various methods are used to reduce the impact of x-rays on healthy tissues. The beams are directed at an angle in such a way that a tumor is in the zone of their intersection (due to this, the main absorption of energy occurs just there). Sometimes the procedure is performed in motion: the patient's body rotates relative to the radiation source around an axis passing through the tumor. At the same time, healthy tissues are in the irradiation zone only sometimes, and the sick - all the time.
X-rays are used in the treatment of certain arthrosis and similar diseases, as well as skin diseases. In this case, the pain syndrome is reduced by 50-90%. Since the radiation is used in this case is softer, side effects similar to those that occur in the treatment of tumors are not observed.